There are two fundamentally different ways to borrow against your Bitcoin without selling it, and they get lumped together under one label far too often. You can borrow from a company (centralized finance, or CeFi) or from a protocol (decentralized finance, or DeFi). The mechanics, the costs, and the question of who can take your Bitcoin are different in each. With Coinbase now offering a Bitcoin-backed loan that is DeFi under the hood, the distinction has gone from academic to something every borrower should understand before clicking "borrow."
This guide lays out both models in plain terms, side by side, and ends with a simple way to decide. It is not advice, and it is not a recommendation of one model over the other.
The one difference everything else flows from
Strip away the jargon and there is a single question underneath all of it: who holds your Bitcoin while you owe money against it?
In CeFi, a company does. It underwrites you, takes or arranges custody of your collateral, and lends you dollars. The trust sits with an institution: you are betting it stays solvent, honest, and competent. In DeFi, a smart contract does. Your collateral sits in code that anyone can inspect on a block explorer, and the rules execute automatically. The trust sits with the software and the people who wrote and audited it.
Almost every other difference, the rate, the speed, the KYC, the way liquidation works, the kind of money you receive, is downstream of that one choice. So start there, then read the rest of this comparison through it.
CeFi vs DeFi, side by side
Native bitcoin vs wrapped bitcoin
Here is the difference almost no one explains clearly, and it matters more than the rate.
Native bitcoin lives on the Bitcoin network. It cannot directly interact with the smart contracts that power DeFi lending, which run on other chains like Ethereum or Base. So to borrow in DeFi, your Bitcoin first has to be converted into a wrapped token, a one-to-one stand-in such as cbBTC (Coinbase) or WBTC that those contracts can actually hold.
CeFi path
Stays native bitcoin
The lender (or its custodian) holds your actual BTC on the Bitcoin network. Nothing is converted. The trust is in the company.
DeFi path
Wrapped to a token
Bitcoin can't talk to smart contracts, so it is converted 1:1 to a wrapped token (cbBTC, WBTC) that the protocol can hold. The trust is in the code and the wrapper.
A CeFi lender does not need this step. It can hold your real bitcoin on the Bitcoin network, full stop. That has three consequences worth weighing. First, a wrapped token is an extra thing to trust: it is only as good as the entity or mechanism that issues and backs it. Second, the wrap is usually free and one-to-one, so it is not a cost so much as a dependency. Third, the conversion has a tax wrinkle covered below. None of this makes DeFi wrong, but "your bitcoin never leaves the Bitcoin network" is a genuine CeFi advantage that the rate comparison alone hides.
Rates: why DeFi looks cheaper, and the catch
DeFi lending rates often sit below CeFi rates, and that is the headline most comparisons stop at. The catch is in how the rate behaves. A DeFi rate is variable, set by supply and demand in the lending market and updated roughly every block, with no published ceiling. The 5% you borrow at today can be 9% next month if demand spikes. CeFi rates are usually fixed or lender-set for the term, which costs a little more but removes the surprise.
So the honest comparison is not "DeFi is cheaper." It is "DeFi is often cheaper right now, and it floats." For where CeFi rates actually stand across lenders today, including the lowest and median APR we track, see the BOB Bitcoin Loan Rate Index. And whichever model you are weighing, compare the all-in effective APR, not the headline number, because fees change the real cost on both sides.
Liquidation: a cure window vs instant code
This is the most material risk difference, and the one borrowers underestimate.
When your loan-to-value climbs too high, both models can sell your collateral. But they do it differently. Most CeFi lenders give you a cure window, a defined period to add collateral or repay before anything is sold, and a team you can reach. DeFi liquidation is enforced by code: once the on-chain price crosses the threshold, the contract liquidates the position automatically and immediately, with a penalty and no human grace period. There is no one to call to buy you an afternoon.
If you are the kind of borrower who would want a phone call and a day to react in a crash, that is a CeFi feature you are paying for. If you would rather the rules be mechanical and unbreakable, that is a DeFi feature. Read our explainer on margin calls and liquidation for how the thresholds work.
Dollars vs a stablecoin
A CeFi loan pays you US dollars. A DeFi loan pays you a stablecoin such as USDC. If you need to wire a down payment, cover a tax bill, or pay a contractor, dollars are simpler, and converting a stablecoin to spendable dollars is an extra step with its own considerations. If you are operating on-chain anyway, a stablecoin may be exactly what you want. It is a small-sounding difference that decides which model is practical for your actual use.
KYC, speed, and privacy
CeFi requires identity verification (KYC and AML), which is why funding takes days and why there is a paper trail. DeFi protocols typically require none, which is why funding can happen in minutes. That cuts both ways: no KYC means speed and privacy, but it also means no institution standing behind the transaction and no help if you make a mistake. For some borrowers the KYC is a feature (it comes with consumer protections); for others it is friction worth avoiding.
The risk you are actually choosing between
Both models are risky. They are just risky in different places.
CeFi concentrates counterparty risk. If the company fails, is hacked, or has quietly re-lent your collateral, your bitcoin can be caught up in it. The 2022 collapses of Celsius, BlockFi, and Voyager were CeFi failures, and they are why we surface custody and rehypothecation on every lender first. A CeFi lender that uses a qualified custodian and does not rehypothecate has addressed much of this, but you are still trusting an institution.
DeFi removes the company but adds smart-contract and oracle risk: a bug in the code, or a manipulated price feed, can cause losses that no support desk will reverse. The collateral is transparent and verifiable, which is a real strength, but the transparency does not protect you from a flaw in the system itself.
Neither risk is strictly larger. The question is which one you would rather hold.
Tax
On tax, the two models start in the same place: borrowing against Bitcoin generally is not a taxable event, because you are not selling. The DeFi wrinkle is the wrapping step. Converting BTC to a wrapped token like cbBTC is commonly treated as non-taxable, but it is not entirely settled, and a liquidation is a disposition of your crypto that can be taxable. Read our guide on whether borrowing against Bitcoin is taxable, and confirm your situation with a CPA. This is not tax advice.
Regulation
CeFi lenders operate under varying degrees of regulatory oversight, which can mean licensing, disclosures, and some consumer protection, along with the obligations that come with it. DeFi protocols are largely unregulated; the code is the rulebook. Regulation is not the same as safety, and oversight did not save the 2022 CeFi lenders, but it does change who you can turn to and what recourse exists if something goes wrong.
So which should you choose?
Lean CeFi if
- You want US dollars in your bank, not a stablecoin
- You want a fixed or predictable rate
- You value a cure window and a human to call
- You are funding a home, business, or tax bill
- You prefer a regulated counterparty
Lean DeFi if
- You want the lowest rate and will watch a variable one
- You are comfortable on-chain and with a stablecoin
- You want funding in minutes with no KYC
- You value verifiable, non-rehypothecated collateral
- You can actively manage liquidation risk yourself
The shorter version: choose CeFi when you want dollars, predictability, and a human in the loop, and DeFi when you want the lowest available rate, speed, no KYC, and verifiable collateral, and you are comfortable managing a variable rate and automatic liquidation yourself. Many borrowers use both.
Where Coinbase fits
Coinbase's loan is the clearest example of why the line blurs. It carries the Coinbase brand but is built on the Morpho protocol on Base: your BTC is wrapped to cbBTC, you receive USDC, the rate floats, and liquidation is automatic on-chain. It is DeFi wearing a familiar face. We cover the specifics, the genuinely attractive parts and the catches, in our Coinbase Bitcoin loan review.
How we cover each on this site
Our comparison table focuses on US CeFi lenders, because they are directly comparable: dollar loans with published rates, defined terms, and a custody model that maps cleanly across lenders. DeFi products like Coinbase's USDC loan do not slot into that table honestly (different payout, a floating rate, and smart-contract custody rather than a company), so we cover them editorially, like this. For where CeFi rates stand right now, the BOB Bitcoin Loan Rate Index tracks the lowest and median APR across the lenders we cover, updated daily. To understand the collateral risk behind either model, start with our glossary entries on rehypothecation and liquidation.